A Brief Note on Giant Cell Tumor of Bone

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A Brief Note on Giant Cell Tumor of Bone

GCTB is the most challenging benign bone tumors. On the other hand, the natural history of this bony tumor may be different from local bony lesion to local metastasis, even malignant transformation which is rare. Symptoms are highly variable and may range from asymptomatic in some patients, joint pain in tumor near the joint and even pathologic fracture. In long-term follow op swelling or palpa...

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Giant cell tumor of the sphenoid bone

Background: Giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull. Giant cell tumor (GCT) of the sphenoid bone is relatively rare. In this report, we describe a tumor of the greater wing of left sphenoid bone. Case presentation: A 31-year-old female was presented with headache, proptosis and diplopia of her left eye. Cranial magnetic resonance ima...

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Giant Cell Tumor of Bone - an Overview

  Giant Cell tumors (GCT) are benign tumors with potential for aggressive behavior and capacity to metastasize. Although rarely lethal, benign bone tumors may be associated with a substantial disturbance of the local bony architecture that can be particularly troublesome in peri-articular locations. Its histogenesis remains unclear. It is characterized by a proliferation of mononuclear stromal ...

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giant cell tumor of bone - an overview

giant cell tumors (gct) are benign tumors with potential for aggressive behavior and capacity to metastasize. although rarely lethal, benign bone tumors may be associated with a substantial disturbance of the local bony architecture that can be particularly troublesome in peri-articular locations. its histogenesis remains unclear. it is characterized by a proliferation of mononuclear stromal ce...

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Secondary Malignant Transformation of Giant Cell Tumor of Bone: Is It a Fate?

The malignant transformation of conventional giant cell tumor of bone (GCTOB) is rare and usually occurs with irradiation. Here we report two neglected cases of conventional GCTOB with spontaneous malignant transformation at 11 and 16 years after initial diagnosis. In the former case, the patient refused to receive any treatment following the incisional biopsy, and in the latter, the firs...

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ژورنال

عنوان ژورنال: MOJ Orthopedics & Rheumatology

سال: 2017

ISSN: 2374-6939

DOI: 10.15406/mojor.2017.07.00273